Showing posts with label COVID-19. Show all posts
Showing posts with label COVID-19. Show all posts

Wednesday, December 22, 2021

Beat Omicron, Get Vaxxed

                                                 

In this updated look at the Covid-19 vaccine we examine its rollout, one year ago. Now with the Omicron variant ravaging the world, getting the vaccine is more important than ever.  Stubborn resistance continues...and Covid variations will continue to happen unless we get everyone vaxxed.

How did that COVID-19 vaccine happen so fast? 

Years, even decades of research brought us to yesterday, the initial rollout of a vaccine for COVID-19, the most disastrous public health calamity in modern times.

In layman's terms, the Pfizer and Moderna vaccines are all about genetics, DNA, and cell biology. The vaccine utilizes our genetic processes and what they do...which is to create life in our bodies and in all living things. We lay people have known about genetics since high school, when we studied a little bit about Gregor Mendel and his experiments with peas. Mendel discovered the basic principles of heredity and laid the mathematical foundation of the science of genetics. 

What James D. Watson and Francis Crick discovered by 1953, and which revolutionized biology and medicine, was how each of our 30 trillion cells (except for mature red blood cells) is able to pack inside its nucleus the 20,000 genes that serve as the instruction manual for us and for all living things.

DNA, deoxyribonucleic acid, is the material from which the 46 chromosomes in each cell's nucleus are formed. DNA contains the codes for the body's approximately 20,000 genes, which govern all aspects of cell growth and inheritance. Watson and Crick discovered that DNA has a double helix structure--two intertwined strands resembling a spiraling ladder. A gene is a distinct section of that DNA and contains the codes for producing specific proteins involved in our body function. In a very short-handed description, genes send information to single-strand structures called messenger RNA (messenger ribonucleic acid). It is the messenger RNA that leaves the cell's nucleus and begins the process of protein building, the essential work of life.

What the scientists and doctors at Pfizer accomplished was to harness the messenger RNA of the Corona-19 virus, which is the active agent of the of the corona virus. The scientists made a synthetic copy of the virus's messenger RNA instead of using a section of living, or dead, virus as has been typically done in previous vaccines. Also, it has been reported that the Pfizer and the Moderna vaccines are less risky to the body and easier to make in mass doses...qualities much needed in an unprecedented pandemic.

As noted scientist and Nobel laureate Leon Cooper said, our investment in basic scientific research must be generous and ongoing. Advances that led to the creation of the personal computer, for example, relied on previous research on transistors, which relied on previous research in basic physics. Had the revolution in our understanding of genes and cellular biology not stood where it is, these vaccines, providing hope to a despairing world, would not have been possible.

Contents 

FOREWORD: HOW A TINY VIRUS CHANGED THE WORLD…..1. LET'S GET BACK TO NORMAL, WHEREVER POSSIBLE….2. THIS IS NOT THE SEASONAL FLU-- IT'S MUCH MORE DANGEROUS….. 3. OUR LUNGS AND COVID-19: A CLOSER LOOK…..4. HOW DID THE COVID-19 VACCINES GET DEVELOPED SO FAST?.....5. THE VACCINES ARE SAFE: THE ROLE OF CLINICAL TRIALS…..6. IMMUNITY: A SMART SYSTEM AND ITS SECRETS…..7. A POWERFUL ACHIEVEMENT: DR. JONAS SALK CONQUERS POLIO…. 8. TAKE PART IN HISTORY...BE THE CHANGE YOU WANT TO SEE HAPPEN….. 9. SCIENCE SAVES MONEY, SAVES LIVES…..10. THE AGE OF THE GENOME BODES WELL FOR HUMAN HEALTH…..11. FAQS ABOUT THE COVID-19 VACCINES EPILOGUE: LIVING UNDER THE UNIQUE STRESS OF A PANDEMIC 


Online review:

"You might have read articles here and there about the Covid vaccines and the miracle of their development in less than a year. But here in book form, all the ingredients of this remarkable story are brought together in one place by author Dave Balog. Mr. Balog has a medical background, but he writes in clear, easy-to-understand prose that any reader will appreciate.

"Specifically, fundamental questions about the virus and the vaccines are answered in the book such as how did the vaccines get developed in record time, how was safety ensured -- particularly given the speed involved -- and the implications not only for the management of future pandemics, but also for overall public health in general.

"Mr. Balog's book is titled, "Get The Covid-19 Vaccine ASAP." Many people, but by no means everyone, know this. The nine chapters, however, explain why vaccination is so urgent in the face of a still evolving disease, the dimensions of which are detailed therein in no uncertain terms."


                                               


About the author 

David Balog, a freelance science/medical writer, served as an editor at the Charles A. Dana Foundation from 1995-2006. There he worked for William Safire, language columnist for the New York Times. David created, wrote, and edited the Dana Sourcebook of Brain Science through four editions. More than 50,000 copies were distributed to elementary schools, middle schools, colleges and to professionals and the general public. He worked with leading brain scientists and doctors, including Nobel laureates. David was also a contributing editor of the Dana Sourcebook of Immunology. and has created the Healing the Brain series of books and videos. Please visit www.HealingTheBrainBooks.Com to learn more. David is a graduate of Hamilton College, where he received a BA in History.



Wednesday, October 6, 2021

A new tool to fight COVID soon?

Wikimedia.com

The announcement that a pill from Merck and partner Ridgeback Biotherapeutics kept Covid patients out of the hospital made headlines and moved stocks late last week. But as is so often true when data are released by press release, there are still many questions left unanswered.

Doctors are excited about the medicine, molnupiravir, because a regimen of pills, even one that involves taking several pills twice a day for five days, should be far easier to deliver to patients than current antiviral Covid-19 treatments, which must be given intravenously. But it’s still unclear how widely this treatment will be used. There will also be debate among financial analysts at investment banks regarding exactly how many billions of dollars in sales the new drug will generate.



Here are some things to keep in mind as we learn more about molnupiravir and about other Covid-fighting pills in development at other companies.

How many other anti-Covid pills will end up proving effective?

One of the reasons that the success of molnupiravir is such a big deal is that there were questions as to whether an antiviral pill could help Covid-19 patients if given early enough. This medicine certainly did, reducing hospitalizations by 50%; it also appeared to have an impact on whether patients survived. That makes it a game-changer. Its success also ups the odds that other medicines will prove effective, too.

Wednesday, September 15, 2021

In Case You Missed It...9/15

These are the most dangerous of times and we have to stay informed. Sometimes we're so busy and the news is overwhelming. Here's a digest of stories you may have missed. Or that the news skipped.


CALIFORNIA


GAVIN NEWSOM BEATS REPUBLICAN RECALL


REPUBLICANS ARE LAYING THE GROUNDWORK TO LIE THAT THE CALIFORNIA RECALL WAS STOLEN

 

THE FIGHT FOR DEMOCRACY

WOODWARD/COSTA BOOK DETAILS REPUBLICAN DESPERATION OVER TRUMP

DEMOCRATIC VOTING BILL DROPS, TWEAKS PROVISIONS; PRESSURE MOUNTS

RELATED – NORM EISEN AND NORM ORNSTEIN: SEVEN REASONS TO THINK SENATE DEMOCRATS WILL ACTUALLY CHANGE THE FILIBUSTER

REPUBLICANS ARE SETTLING ON A STRATEGY FOR ALL THEIR ELECTION LOSSES: ‘IT WAS RIGGED!’

US CAPITOL RAMPING UP SECURITY; TEMPORARY FENCING AROUND CAPITOL TO RETURN AHEAD OF SEPTEMBER 18 RIGHT-WING RALLY

GEORGE W. BUSH 2001: MEET GEORGE W. BUSH 2021

 

LET’S BUILD BACK BETTER


HOUSE DEMOCRATS’ PLAN TO TAX THE RICH FOCUSES ON INCOME, WHILE LEAVING WEALTH GAINS & INHERITANCES ALONE – FOR NOW

SARGENT & WALDMAN: LET’S STOP PRETENDING BIDEN’S PROPOSED TAX INCREASES ON THE RICH ARE RADICAL

THIS REPUBLICAN GOVERNOR NAILS ANTi-VAXXERS

Credit: RandiRhodes.com


 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Watson-Crosby, former president, National Association of Former Foster Children

Sunday, May 23, 2021

Is your state getting vaccinated?

 

Find out where your state ranks in vaccine rates.

This week, CNN ranked the states by order of percentage of residents who have received at least one Covid-19 vaccine dose.


The numbers can be looked at in several ways, but they are falling short, in some states very short, of the goals for herd immunity, i.e., community immunity. President Biden has set a goal to have 70% of Americans with at least one vaccine dose by early July. 


We need to pull together in this effort, to encourage people to get vaccinated against Covid-19 and then even to get angry that people are ignoring the science and risking the health of their neighbors, friends, and families. 


Get more information for yourself by ordering a copy of the book listed below. 


Here are the states and their vaccination rates as of May 19th.


  1. Maine 50.12% 
  2. Connecticut 49.29% 
  3. Vermont 48.39% 
  4. Rhode Island 47.97% 
  5. Massachusetts 47.68% 
  6. New Jersey 45.16% 
  7. New Mexico 44.92% 
  8. Hawaii 44.68% 
  9. Maryland 43.66% 
  10. New York 43.44% 
  11. Minnesota 42.41%, 
  12. Wisconsin 42.05% 
  13. Colorado 41.94% 
  14. District of Columbia 41.54% 
  15. Virginia 41.32% 
  16. Washington 41.28% 
  17. South Dakota 41.25% 
  18. Iowa 41.22% 
  19. Pennsylvania 40.11% 
  20. Nebraska 39.98% 
  21. Oregon 39.98% 
  22. Delaware 39.81% 
  23. California 39.33%, 
  24. Michigan 39.25% 
  25. Maryland 38.90%
  26. Ohio 38.14% 
  27. Alaska 38.04% 
  28. New Hampshire 37.93%
  29. Illinois 37.11% 
  30. Kansas 36.71%
  31. Kentucky 36.56% 
  32. Montana 36.55% 
  33. Florida 36.15% 
  34. North Dakota 35.33% 
  35. North Carolina 34.42% 
  36. Nevada 34.25% 
  37. Texas 33.06% 
  38. West Virginia 33.02%
  39. Indiana 32.99% 
  40. Missouri 32.83% 
  41. Oklahoma 32.58% 
  42. South Carolina 31.97%  
  43. Idaho 31.16% 
  44. Wyoming 30.6% 
  45. Utah 30.22% 
  46. Tennessee 30.17% 
  47. Louisiana 29.88% 
  48. Georgia 29.53% 
  49. Arkansas 29.5% 
  50. Alabama 27.79% 
  51. Mississippi 26.24%

Learn more about the vaccine, about Covid-19 and about public health in this new book:

Monday, May 17, 2021

Now the road to community immunity begins

Full community immunity may rely on outreach.


The first 90 million Americans to get vaccinated may be the easy part. Now begins the long road to reach 75%, at which herd immunity (I like the term community immunity much better) can be reached. But now it turns out according to a study from Brown University that the problem may not be hardened hearts but lack of information about where to get vaccinated and how and by whom.

In other words, don't overthink things.


Stefanie Friedhoff is a professor of the practice in health services, policy, and practice as well as strategy director at Brown University School of Public Health.


She writes in her blog:


"I lead a team at Brown University School of Public Health that is undertaking new research in partnership with the Rockefeller Foundation and community organizations across the U.S. to understand people’s experiences regarding vaccination, public health, and the health care system more generally, rather than just their intentions about this specific vaccine. What we have learned so far from this survey, fielded by HIT Strategies in communities of color in five U.S. cities, is telling: Even though a majority of Black and Latino Americans want to get vaccinated — 72% in this survey — a surprising 63% said they didn’t have enough information about where to get the shot. In addition, more than 20% said they had regularly been treated with disrespect when getting health care in the past, and 20% said they have had trouble finding health care when needed.


"Despite these systemic barriers, only 3% of the total sample said that nothing at all would move them to get the Covid-19 vaccine.


"Everyone else, even those who said 'no' to getting a vaccine now, listed reasons that would motivate them to get a shot, such as 'seeing a person I trust get the vaccine' or having 'a vaccination site close to my home.'


"In fact, 'having more information' is the single most important concern expressed by those unsure about the Covid-19 vaccine, according to almost every poll that asks this question. This is true across the political spectrum. Blaming conservative Americans for taking their time or for believing lies, and labeling them as hesitant or resisters only hardens their viewpoints. Instead, the public health community needs to come to grips with what motivates people, and also with the harmful impact of misinformation on Americans who do not have access to quality information.


"It’s still a long road to getting most Americans vaccinated against Covid-19. It can be shortened by worrying less about today’s confidence polls and more about persistent barriers to vaccination. The health and public health communities need to continue the hard work of making vaccines ubiquitous and available without complex sign-up procedures — at churches, grocery stores, barber shops, food pantries, and yes, even in bars and restaurants.


"People’s questions must be answered and false narratives preempted by flooding online and offline spaces with high-quality information in the languages people speak on the platforms they frequent. Concerted effort is needed to expose misinformation tactics and how they are unleashed to generate confusion, as well as to regulate the platforms that empower them.


"For most Americans — and that includes conservatives — who are given the chance to discuss vaccination on their own terms and timelines and for whom vaccination is easy, nearby, and supported by employers, the question shifts from if they will get vaccinated to when and how."


Learn more about the vaccine, about Covid-19 and about public health in this new book:




Friday, May 14, 2021

52 years later: Separate and unequal, still

President Lyndon Johnson, center, organized the Kerner Commission in 1968. It concluded that America contained two societies, one White, one Black, separate and unequal.

Two friends, both Black, informed me that they will not be getting the COVID-19 vaccine. (Full disclosure: I did share my book with both.) I was angry and then sad, not just that I couldn't persuade them but how deep seated their animosity was toward getting vaccinated.


After a day I've realized there's no use in continuing a conversation. They've made up their minds and their decisions and the reasons for them are far beyond a book about a vaccine.


Their decisions brought me back to when I studied the Kerner Commission, which was created by President Johnson following inner-city protests in 1967 in Newark, New Jersey, Detroit and more than 25 other cities across America. The Kerner Commission's findings were stunning and went where no other such panel had gone before, using social science research that had been ignored.


The commission concluded, 52 years ago, that America was split into two societies, one Black, one White, separate and unequal, and steadily moving apart. Johnson's appointees got it right. For the first time an official panel looked at factors such as the police, institutional racism, and lack of opportunity among black Americans. 


But nothing has substantially changed.


So when one of my black friends said that she did not trust "white medicine," there really was nothing for me to say. All I had to think about was that Black woman doctor who documented by video her treatment as she lay in a hospital bed fighting COVID-19. She was ignored, her pain was denied, and her treatments were delayed. And she knew the protocols and how she was being denied them. Shortly after her last video, this doctor died.


So my optimism in the mRNA vaccines for COVID-19 that are saving lives and will end this pandemic is tamped down today by the realization that this society is deeply divided and that African-Americans feel woefully unequal and distrustful of a system they view as other.


But I'm grateful to my friends for at least reading my book. Perhaps progress will come, just at glacial speed. I did not know how badly they feel.


Now I do.

Learn more about the vaccine, about Covid-19 and about public health in this new book:





Wednesday, May 12, 2021

The road from Chicago to food and drug safety


In 1906, The Jungle, by Upton Sinclair, shocked Americans about a dangerous lack of food safety.

Mary had a Little Lamb

And when it began to sicken,

She sent it to Chicago

Where now it's a can of chicken.

--Satirist on The Jungle by Upton Sinclair


Supposedly over dinner one night in the White House, President Theodore Roosevelt was glancing through an advanced copy of The Jungle, the muckraking novel of scurrilous practices by the nation's meat producers. 

Dead rats, Sinclair wrote, were winding up in hot dogs, for example.

Roosevelt dropped his fork and exclaimed, "I'm pizzened!" 

In short order in 1906, Roosevelt pushed for and passed a meat inspection law and the Pure Food and Drug Law.

These acts led to the creation of the Food and Drug Administration, which conducts rigorous tests and enforces strict protocols on products introduced to Americans via processed foods, new drugs, and new medical procedures. 

The Covid-19 vaccines had to pass rigorous tests involving hundreds of thousands of volunteers. The testing is arduous and conducted with strict safety in mind. 

Learn more about the vaccine, about Covid-19 and about public health in this new book:


Monday, May 10, 2021

Distillery milk and Covid vaccine safety

Distillery milk, or swillmilk, poisoned and killed New York City children in the late 1800s. This and other scams led to today's Food and Drug Administration (FDA) to protect American health.

Among the many reasons I've found for vaccine hesitancy, probably the most common one is whether it's safe. How can a vaccine, people ask, be developed so quickly? They must have taken shortcuts. 

Well the "they" in this instance is the Food and Drug Administration, the FDA, which we hear talked about so often when news of the vaccine and its development and implementation is given over TV, the Internet, radio, etc. Now the FDA is more than 100 years old and has a very interesting history in protecting the health of Americans from new drugs, new food additives, or any medical device and procedure that is made available to the general public. 

In the late 1800s health standards were so low or non-existent that there existed a dangerous type of milk, more poison than food, that was delivered to children of New York City.

Devious dairy farmers and makers of grain alcohol combined to produce a concoction known as distillery milk. The scheme work this way: after grain alcohol was produced, there remained a weak yet slightly nutritious type of mash. The unscrupulous businessmen thought that this gruel could be given to dairy cows, which were producing milk in the borough of Brooklyn... remember this was the late 1800s.

The distillery owners and the dairy farmers got together, literally moving their plants next to each other to save every penny for their scam. The barely nutritious mash left over from the alcohol production was sent next door to the dairy cows. There the emaciated cows produced thin, blue colored milk, almost completely lacking in nutrition. 

To fix the color, the dairies added chalk. To thicken it, they added Plaster of Paris. Thus was born "distillery milk," also know as "swillmilk."

Children around New York City, particularly in Manhattan, were given this poison in schools, got sick, and died. An investigation by the private New York Academy of Sciences unveiled the scheme, and it was eventually stopped. 

So bad was the need for regulation that the federal Department of Agriculture began an investigation and by 1906, with the backing of President Theodore Roosevelt, the Pure Food and Drug law was enacted. With that law came the establishment of the Food and Drug Administration.

So while nothing is certain in this world, the presence and the rigorous testing and precautions of the FDA give us a sense of safety and security. Clinical trials are the gold standard for drugs. foods, and any medical devices or procedures. The Covid vaccines underwent rigorous four-step clinical trials, that were only speeded up by the vaccine makers who took the gamble that they could conduct several of these steps, at their own financial risk, at the same time. So sure were they that the vaccines would prove safe and effective that manufacturing actually began before the vaccines had received complete approval. The vaccines however could not be released to the public until that approval was granted by the food and drug administration.












Tuesday, April 20, 2021

Covid-19 FAQs: Protect yourself

This page uses the official term COVID-19 to refer to the disease caused by the 2019 novel coronavirus.


Many rumors related to COVID-19 circulating on social media are false or contain misinformation. People should be skeptical of rumors they hear on social media that aren’t being reported by reputable health organizations or mainstream media outlets and should not share or repost items unless they are able to confirm that they are true. False and inaccurate social media posts can cause a great deal of harm.

Source: State of Utah.gov


What are the symptoms of COVID-19?

The most common symptoms reported are fever, cough, and shortness of breath. You may also have muscle aches, a sore throat, or a decrease in your sense of smell or taste. If you have symptoms of COVID-19, call your doctor and isolate right away. Your doctor will decide if you need to be tested. You can find testing locations at https://coronavirus.utah.gov/testing-locations/.

You can use the CDC coronavirus self-checker to help you decide if you need medical care. This tool can be found at https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/symptoms.html.

How long does it take for symptoms to appear?

Symptoms of COVID-19 may appear 2-14 days after exposure. This is why you will be asked to quarantine for 14 days if you are exposed to someone who has COVID-19, because it can take 14 days for you to get sick. If you have symptoms of COVID-19, such as a fever, cough, shortness of breath, muscle aches, sore throat, or a decrease in your sense of smell or taste, call your doctor and isolate right away. Your doctor will decide if you need to be tested.

I was at a place where someone who tested positive for COVID-19 was. Do I need to be tested?

Not necessarily. If you have symptoms of COVID-19 (fever, cough, shortness of breath, muscle aches, sore throat, or a decrease in your sense of smell or taste), you should get tested for COVID-19. Call your doctor and isolate right away.  

If you were in close contact with someone who has tested positive for COVID-19, you should quarantine for 14 days and monitor for symptoms. This means you were closer than 6 feet or 2 meters (about 2 arm lengths) from the person who tested positive for 15 minutes or longer. Public health workers may recommend you get tested for COVID-19 if you were in close contact with someone who has it. This will happen through the contact tracing process. 

Public health workers do contact tracing when someone tests positive for COVID-19. They will contact every person they feel may have been exposed to the virus. If they don't contact you, it means you were most likely not exposed. In the rare cases that public health feels they may not have the ability to contact all of the close contacts of the individual, they will issue a public statement so everyone will know.

What does close contact mean?

Close contact means being within 6 feet or 2 meters (about 2 arm lengths) of someone who has COVID-19 for 15 minutes or longer. Close contact also means having direct contact with infectious secretions of someone who has COVID-19, such as being coughed on. 

What should I do if I am sick?

If you have symptoms of COVID-19, call your doctor and isolate right away. You should also get tested for COVID-19 if you have symptoms. 

Isolation is for people who are sick or have tested positive for COVID-19. Everyone who lives in your house should stay at home if someone in your house tests positive for COVID-19. Isolation is for people who are not sick enough to be in the hospital. Your doctor may tell you to recover at home. Isolation keeps sick people away from healthy people to stop sickness from spreading. 

If you are sick or test positive for COVID-19, you should:

  • Stay home unless you need medical care.
  • Try to stay in a different room than other people in your house. If this is not possible, stay at least 6 feet away from other people.
  • Try to use a different bathroom than the other people who live in your house.
  • Clean surfaces that are touched often (phones, doorknobs, light switches, toilet handles, sink handles, countertops, and anything metal).
  • Do not travel if you are sick.
  • Cover your mouth and nose with a tissue or your sleeve (not your hands) when you cough or sneeze.
  • Wash your hands with soap and water right after you cough, sneeze, or blow your nose. If you do not have soap or water, you can use an alcohol-based hand sanitizer.
  • Wear a face mask if you have to be around other people (if you have to be in the same room or car). If you can’t wear a face mask because it makes it hard for you to breathe, stay in a different room from other people. If people come into your room, they should wear a face mask.

More information on what to do if you are sick can be found at https://www.cdc.gov/coronavirus/2019-ncov/if-you-are-sick/steps-when-sick.html


Should I wear a face mask?

There is clear scientific evidence that wearing a face covering prevents the spread of COVID-19. The CDC recommends all people 2 years of age and older wear a cloth face covering in public settings and when around people who don’t live in your household, especially when it is hard to physical distance. 

While cloth face coverings are strongly encouraged to reduce the spread of COVID-19, it may not be possible in every situation or for some people to wear a face covering. In some situations, a cloth face covering could make a physical or mental condition worse or be a safety concern. Consider adaptations and alternatives whenever possible to help someone wear a face covering or to reduce the risk of COVID-19 spread if it is not possible for someone to wear one.

You can help your community if you make your own mask. There are not enough surgical masks (such as the ones used in doctors’ offices) and N-95 respirators for all of the healthcare workers to take care of patients with COVID-19. Please try to leave these masks for healthcare workers. 

The CDC has more tips and instructions for how to make a homemade mask at https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/diy-cloth-face-coverings.html

Do I need to wear a mask if I have been sick?

You should wear a facemask if you are sick, showing symptoms of COVID-19, or have tested positive for COVID-19 to protect others from the risk of getting infected. 

Can the virus be spread to the children of pregnant women?

Cases have been reported where a pregnant woman with COVID-19 has passed the virus to the baby during pregnancy or delivery. Studies are continuing.

Can the virus be spread to a baby through breastmilk?

There is no information at this time that a mother can spread COVID-19 to her baby through breastmilk. Breastfeeding should be determined by the mother and her doctor. A mother with confirmed COVID-19 should take steps to avoid spreading the virus to her infant, including washing hands, wearing a face mask, and cleaning the breast pump.