Showing posts with label cortisol. Show all posts
Showing posts with label cortisol. Show all posts

Monday, November 11, 2019

Any amount of running linked to significantly lower risk of early death

The brain is at the center of your health. Learn how.


Substantial improvements in population health/longevity

likely if more people took it up, say researchers

November 4, 2019
British Journal of Sports Medicine.
Any amount of running is linked to a significantly lower risk
of death from any cause, finds a pooled analysis
of the available evidence, published online in the
British Journal of Sports Medicine.
If more people took up running -- and they wouldn't have to run far or
fast -- there would likely be substantial improvements in population health and
longevity, conclude the researchers.
It's not clear how good running is for staving off the risk of death from
any cause and particularly from cardiovascular disease and cancer,
say the researchers.

Nor is it clear how much running a person needs to do to reap
these potential benefits, nor whether upping the frequency,
duration, and pace -- in other words, increasing the 'dose' --
might be even more advantageous.

To try and find out, the researchers systematically reviewed relevant
published research, conference presentations, and doctoral theses
and dissertations in a broad range of academic databases.

They looked for studies on the association between running/jogging
and the risk of death from all causes, cardiovascular disease, and cancer.
They found 14 suitable studies, involving 232,149 people,
whose health had been tracked for between 5.5 and 35 years.
During this time, 25,951 of the study participants died.
When the study data were pooled, any amount of running was
associated with a 27% lower risk of death from all causes
for both sexes, compared with no running.
And it was associated with a 30% lower risk of death
from cardiovascular disease, and a 23% lower risk of death from cancer.
Even small 'doses' -- for example, once weekly or less, lasting
less than 50 minutes each time, and at a speed below
6 miles (8 km) an hour, still seemed to be associated
with significant health/longevity benefits.

So running for 25 minutes less than the recommended weekly
duration of vigorous physical activity could reduce the risk of death.
This makes running a potentially good option for those whose main
obstacle to doing enough exercise is lack of time, suggest the researchers.
But upping 'the dose' wasn't associated with a further lowering
of the risk of death from any cause, the analysis showed.
Nevertheless, they suggest that any amount of running is
better than none, concluding: "Increased rates of participation in
running, regardless of its dose, would probably lead to
substantial improvements in population health and longevity."
The brain is at the center of your health. Learn how.



Story Source:
Materials provided by BMJ. Note: Content may be edited for style and length.


Friday, November 8, 2019

Stressed to the max? Deep sleep can rewire the anxious brain


Learn how the brain controls stress. 

A sleepless night can trigger up to a 30 percent rise in emotional

stress levels, new study shows

:
November 4, 2019:
University of California - Berkeley
Researchers have found that the type of sleep most apt to calm and reset the anxious brain
is deep sleep, also known as non-rapid eye movement (NREM) slow-wave sleep, a state in
which neural oscillations become highly synchronized, and heart rates and blood pressure drop.
Deep sleep concept (stock image). | Credit: © stokkete / stock.adobe.com
Deep sleep concept (stock image).
Credit: © stokkete / Adobe Stock
When it comes to managing anxiety disorders, William Shakespeare's
Macbeth had it right when he referred to sleep as the "balm of hurt minds."
While a full night of slumber stabilizes emotions, a sleepless night can trigger
up to a 30% rise in anxiety levels, according to new research from the
University of California, Berkeley.
UC Berkeley researchers have found that the type of sleep most apt to calm and reset
the anxious brain is deep sleep, also known as non-rapid eye movement (NREM) slow-wave
sleep, a state in which neural oscillations become highly synchronized, and heart rates and
blood pressure drop.
"We have identified a new function of deep sleep, one that decreases anxiety overnight
by reorganizing connections in the brain," said study senior author Matthew Walker,
a UC Berkeley professor of neuroscience and psychology. "Deep sleep seems to be a
natural anxiolytic (anxiety inhibitor), so long as we get it each and every night."
The findings, published today, Nov. 4, in the journal Nature Human Behaviour,
provide one of the strongest neural links between sleep and anxiety to date. They
also point to sleep as a natural, non-pharmaceutical remedy for anxiety disorders,
which have been diagnosed in some 40 million American adults and are rising among
children and teens.
"Our study strongly suggests that insufficient sleep amplifies levels of anxiety and,
conversely, that deep sleep helps reduce such stress," said study lead author
Eti Ben Simon, a postdoctoral fellow in the Center for Human Sleep Science at UC Berkeley.
In a series of experiments using functional MRI and polysomnography, among other measures,
Simon and fellow researchers scanned the brains of 18 young adults as they viewed
emotionally stirring video clips after a full night of sleep, and again after a sleepless night.
Anxiety levels were measured following each session via a questionnaire known as the
state-trait anxiety inventory.
After a night of no sleep, brain scans showed a shutdown of the
medial prefrontal cortex, which normally helps keep our anxiety in check,
while the brain's deeper emotional centers were overactive.
"Without sleep, it's almost as if the brain is too heavy on the emotional accelerator
pedal, without enough brake," Walker said.
After a full night of sleep, during which participants' brain waves were
measured via electrodes placed on their heads, the results showed their anxiety
levels declined significantly, especially for those who experienced more slow-wave
NREM sleep.
"Deep sleep had restored the brain's prefrontal mechanism that regulates our emotions,
lowering emotional and physiological reactivity and preventing the escalation of anxiety,"
Simon said.
Beyond gauging the sleep-anxiety connection in the 18 original study participants,
the researchers replicated the results in a study of another 30 participants.

Across all the participants, the results again showed that those who got more
nighttime deep sleep experienced the lowest levels of anxiety the next day.
Moreover, in addition to the lab experiments, the researchers conducted an
online study in which they tracked 280 people of all ages about how both their sleep and
anxiety levels changed over four consecutive days.
The results showed that the amount and quality of sleep the participants got from
one night to the next predicted how anxious they would feel the next day. Even subtle
nightly changes in sleep affected their anxiety levels.
"People with anxiety disorders routinely report having disturbed sleep, but rarely is
sleep improvement considered as a clinical recommendation for lowering anxiety,"
Simon said.


Learn how the brain controls stress. 

"Our study not only establishes a causal connection between sleep and anxiety, but it
identifies the kind of deep NREM sleep we need to calm the overanxious brain."
On a societal level, "the findings suggest that the decimation of
sleep throughout most industrialized nations and the marked escalation in anxiety
disorders in these same countries is perhaps not coincidental, but causally related,"
Walker said. "The best bridge between despair and hope is a good night of sleep."
Co-authors of the study are Aubrey Rossi and Allison Harvey, both at UC Berkeley.


Story Source:
Materials provided by University of California - Berkeley. Original written by Yasmin Anwar.

Wednesday, October 30, 2019

Coping with the Death of a Parent


The Death of a Parent Affects Even Grown Children Psychologically and Physically

Grief is both real and measurable. Scientists now know that losing a parent changes us forever.

By Joshua A. Krisch
Updated Oct 16 2019, 11:00 AM

The death of a parent is one of the most emotional and universal human experiences. If a person doesn’t know what it’s like suffer the loss of a father or mother, they most likely will one day. But just because the passing of a parent happens to almost everyone doesn’t make it any easier. The death of a parent is traumatic, yes, but it also informs and changes their children biologically and psychologically. It can even make them sick.

The death of a parent can trigger emotional and physical stress. Click here to learn more.

“In the best-case scenario, the death of a parent is anticipated and there’s time for families to prepare, say their goodbyes, and surround themselves with support,” psychiatrist Dr. Nikole Benders-Hadi says. “In cases where a death is unexpected, such as with an acute illness or traumatic accident, adult children may remain in the denial and anger phases of the loss for extended periods of time … [leading to] diagnosis of major depressive disorder or even PTSD, if trauma is involved.”

There’s no amount of data that can capture how distinctly painful and powerful this grief is. That said, there are a number of psychological and brain-imaging studies that demonstrate the magnitude of this loss. The posterior cingulate cortex, frontal cortex, and cerebellum are all brain regions mobilized during grief processing, research shows. These regions are involved in storing memories and dwelling on the past, but they’re also involved in regulating sleep and appetite.

In the short term, neurology assures us that loss will trigger physical distress. In the long-term, grief puts the entire body at risk. A handful of studies have found links between unresolved grief and hypertension, cardiac events, immune disorders, and even cancer. It is unclear why grief would trigger such dire physical conditions, but one theory is that a perpetually activated sympathetic nervous system (fight or flight response) can cause long-term genetic changes. These changes — less pre-programmed cell death, dampened immune responses — may be ideal when a bear is chasing you through the forest and you need all the healthy cells you can get. But this sort of cellular dysregulation is also how cancerous cells metastasize, unchecked. 

While the physical symptoms are relatively consistent, the psychological impacts are all but unpredictable. In the 12 months following the loss of a parent, the American Psychological Association’s Diagnostic and Statistical Manual of Mental Disorders considers it healthy for adults who have lost their parents to experience a range of contradictory emotions, including sadness, anger, rage, anxiety, numbness, emptiness, guilt, remorse, and regret. It is normal to withdraw from friends and activities; it is normal to throw oneself into work.

As ever, context matters. Sudden, violent death puts survivors at higher risk of developing a grief disorder, and when an adult child has a fractured relationship with a parent, the death can be doubly painful — even if the bereaved shuts down and pretends not to feel the loss. “Coping is less stressful when adult children have time to anticipate parental death,” Omojola says. “Not being able to say goodbye contributes to feeling depressed and angry.” This may explain why studies have shown that young adults are more affected by parental loss than middle-aged adults. Presumably, their parents died unexpectedly, or at least earlier than average.

Gender, of both the parent and child, can especially influence the contours of the grief response.


Studies suggest that daughters have more intense grief responses than sons, but men who lose their parents may be slower to move on. “Males tend to show emotions less and compartmentalize more,” Carla Marie Manly, a clinical psychologist and author, told Fatherly.


At the same time, the differences between losing a father and a mother represent relatively weak trends. “Complicated bereavement can exist no matter which parent is lost,” Benders-Hadi says. “More often, it is dependent on the relationship and bond that existed with the parent.”

Grief becomes pathological, according to the DSM, when the bereaved are so overcome that they are unable to carry on with their lives. Preliminary studies suggest this occurs in about 1 percent of the healthy population, and about 10 percent of the population that had previously been diagnosed with a stress disorder. “A diagnosis of adjustment disorder is made within three months of the death if there is a ‘persistence of grief reactions’ exceeding what’s normal for the culture and the religion,” Omojola says. “In this situation, the grieving adult has severe challenges meeting social, occupational, and other expected, important life functions.” Even adults who are able to go to work and put on a brave face may be suffering a clinical condition if they remain preoccupied with the death, deny that their parent has died, or actively avoid reminders of their parents, indefinitely. This condition, known as persistent complex bereavement disorder, is a trickier diagnosis to pin down (the DSM labeled it a “condition for further study”).

Elisabeth Goldberg works with grieving adults as a relationship therapist in New York City, and she has seen the toll that long-term grieving can take on a marriage. Specifically, Goldberg suggests a (somewhat Freudian) link between losing a parent and cheating on a spouse. “I see many affairs as manifestations of unresolved grief about losing a parent,” Goldberg says. “The adult child stays in a state of disbelief, and rejects reality in many ways in order to feed the delusion that the parent is still alive. The grieving child needs a new attachment figure, that’s the psyche trying to reconcile the denial and grief. 

In more concrete — and dire — terms, unresolved grief can spiral into anxiety and depression. This is especially true when the parent dies by suicide, according to Lyn Morris, a licensed therapist and VP at Didi Hirsch Mental Health Services. “Adults who lose a parent to suicide often struggle with complex emotions such as guilt, anger, and feelings of abandonment and vulnerability,” she told Fatherly. Indeed a 2010 study out of Johns Hopkins University confirmed that losing a parent to suicide makes children more likely to die by suicide themselves.

How to cope in a healthy way remains an active area of scientific inquiry. Ross Grossman, a licensed therapist who specializes in adult grief, has identified several “main distorted thoughts” that infect our minds when we face adversity. 

On the opposite extreme, patients sometimes blame their deceased parents for not treating them properly, and never making amends. This is similarly unhealthy. “The usual result of this is deep resentment, anger, rage,” Grossman says. “They may have genuine, legitimate reasons to feel mistreated or abused. In these situations, it’s not always the death of the parent but the death of the possibility of reconciliation, of rapprochement and apology from the offending parent.”

“The possibility has died along with the person.”
The death of a parent can trigger emotional and physical stress. Click here to learn more.

In extreme cases, therapy may be the only way to get a grieving son or daughter back on his or her feet. But time, and an understanding spouse, can go a long way toward helping adults get through this unpleasant, yet ubiquitous, chapter in their lives. “Husbands can best support their wives by listening,” Manly says. “Men often feel helpless in the face of their wives’ emotions, and they want to fix the situation. A husband can do far more good by sitting with his wife, listening to her, holding her hand, taking her for walks, and — if she desires — visiting the burial site.”

Saturday, October 12, 2019

Your doggie may just extend your life

"Man's best friend" now has even more meaning.


        Date:
October 8, 2019
Source:
American Heart Association
Summary:
Dog ownership was associated with a 33% lower risk of early death for heart attack survivors living alone and 27% reduced risk of early death for stroke survivors living alone, compared to people who did not own a dog. Dog ownership was associated with a 24% reduced risk of all-cause mortality and a 31% lower risk of death by heart attack or stroke compared to non-owners.

Dog ownership may be associated with longer life and better cardiovascular outcomes, especially for heart attack and stroke survivors who live alone, according to a new study and a separate meta-analysis published in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association.
"The findings in these two well-done studies and analyses build upon prior studies and the conclusions of the 2013 AHA Scientific Statement 'Pet Ownership and Cardiovascular Risk' that dog ownership is associated with reductions in factors that contribute to cardiac risk and to cardiovascular events," said Glenn N. Levine, M.D., chair of the writing group of the American Heart Association's scientific statement on pet ownership. "Further, these two studies provide good, quality data indicating dog ownership is associated with reduced cardiac and all-cause mortality. While these non-randomized studies cannot 'prove' that adopting or owning a dog directly leads to reduced mortality, these robust findings are certainly at least suggestive of this."
Full story: Here.

Thursday, September 19, 2019


Health-care providers hold biases based on

sexual orientation, study says

Findings highlight need for more training of

providers in cultural sensitivity

University of Washington Health Sciences/UW Medicine
In the first study that looks at a variety of health-care providers and their implicit attitudes towards lesbian women and gay men, researchers found there is widespread implicit bias toward lesbian women and gay men. The study finds that moderate to strong implicit preferences for straight people over lesbian and gay people are widespread among heterosexual providers.
Learn about the unique stress and
traumas faced by LGBTQ youth.


Findings highlight need for more training of providers in cultural sensitivity

University of Washington Health Sciences/UW Medicine
In the first study that looks at a variety of health-care providers and their implicit attitudes towards lesbian women and gay men, researchers found there is widespread implicit bias toward lesbian women and gay men. The study finds that moderate to strong implicit preferences for straight people over lesbian and gay people are widespread among heterosexual providers.
In the first study that looks at a variety of healthcare providers and their implicit attitudes towards lesbian women and gay men, researchers found there is widespread implicit bias toward lesbian women and gay men.
The study, "Health care providers' implicit and explicit attitudes toward lesbian women and gay men," published in the American Journal of Public Health finds that moderate to strong implicit preferences for straight people over lesbian and gay people are widespread among heterosexual providers. Also lesbian and gay health providers expressed implicit and explicit preferences for lesbian and gay people over straight people. Bisexual providers were found to have mixed preferences, mental health providers held the weakest implicit bias for heterosexual people over lesbian and gay people and nurses held the strongest implicit bias for heterosexual people over lesbian and gay people.
In short, healthcare providers, similar to others in society, hold a bias for people who shared their own sexual identity.
Lead researcher, Janice Sabin, UW research associate professor in biomedical informatics and medical education, said that clinical care of the LGBT population is a somewhat neglected area in curriculum in nursing, medicine and other areas of healthcare education.
"We want all providers to be proficient in treating diverse populations, including the LGBT population," she said.
Rachel G. Riskind with the Department of Psychology at Guilford College in Greensboro, N.C., and Brian A. Nosek with the Department of Psychology at the University of Virginia in Charlottesville, were co-authors on the study.
Researchers used results from the Sexuality Implicit Association Test developed to assess presence of implicit bias towards either heterosexual or homosexual individuals. The test captured demographic data and implicit association test results for more than 200,000 participants between May 2006 and December 2012. Test takers were asked to indicate their explicit preferences towards heterosexual, lesbian and gay people by endorsing statements ranging from "I strongly prefer straight people to gay people to "I strongly prefer gay people to straight people." The study categorized healthcare respondents by their profession ¬¬¬-- medical doctor, nurse, mental health provider, other treatment provider or non-provider --to assess attitudes specifically from healthcare providers.
Test takers voluntarily accessed the Sexuality Implicit Association Test on Project Implicit, a non-profit organization founded in 1998 by three scientists -- Tony Greenwald (University of Washington), Mahzarin Banaji (Harvard University), and Brian Nosek (University of Virginia). Project Implicit provides a "virtual laboratory" for collecting data on the Internet in a mission to educate the public about hidden biases or thoughts and feelings outside of conscious awareness and control.
Sabin said, "training for healthcare providers about treating sexual minority patients is an area in great need of attention."
"For healthcare organizations that aim to serve these populations, these data suggest an opportunity to examine methods likely to mitigate implicit biases, such as eliminating discretion from decision-making, use of clinical guidelines, awareness of personal bias as self-caution, organizational policies that promote objective decision-making, and inclusion of counter-stereotypical experiences in educational programs," the authors conclude.
While this study found implicit bias among healthcare providers, Sabin said future research should examine how providers' implicit and explicit preferences toward sexual orientation affect delivery of care to members of sexual minority populations.



Learn about the unique stress and
traumas faced by LGBTQ youth.