Friday, September 24, 2021

Likely cause of Alzheimer’s disease identified

 

A likely cause of Alzheimer's disease.

Date:

September 15, 2021

Source:

Curtin University


Summary:

Ground-breaking new research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities.'


    

FULL STORY

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for the second-leading cause of death.


The study, published in the PLOS Biology journal and tested on mouse models, identified that a probable cause of Alzheimer's disease was the leakage from blood into the brain of fat-carrying particles transporting toxic proteins.


Lead investigator Curtin Health Innovation Research Institute (CHIRI) Director Professor John Mamo said his collaborative group of Australian scientists had identified the probable 'blood-to-brain pathway' that can lead to Alzheimer's disease, the most prevalent form of dementia globally.


 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Hudson, former president, National Association of Former Foster Children


"While we previously knew that the hallmark feature of people living with Alzheimer's disease was the progressive accumulation of toxic protein deposits within the brain called beta-amyloid, researchers did not know where the amyloid originated from, or why it deposited in the brain," Professor Mamo said.


"Our research shows that these toxic protein deposits that form in the brains of people living with Alzheimer's disease most likely leak into the brain from fat carrying particles in blood, called lipoproteins.


"This 'blood-to-brain pathway' is significant because if we can manage the levels in blood of lipoprotein-amyloid and prevent their leakage into the brain, this opens up potential new treatments to prevent Alzheimer's disease and slow memory loss."


Building on previous award-winning research that showed beta-amyloid is made outside the brain with lipoproteins, Professor Mamo's team tested the ground-breaking 'blood-to-brain pathway' by genetically engineering mouse models to produce human amyloid-only liver that make lipoproteins.


"As we predicted, the study found that mouse models producing lipoprotein-amyloid in the liver suffered inflammation in the brain, accelerated brain cell death and memory loss," Professor Mamo said.


"While further studies are now needed, this finding shows the abundance of these toxic protein deposits in the blood could potentially be addressed through a person's diet and some drugs that could specifically target lipoprotein amyloid, therefore reducing their risk or slowing the progression of Alzheimer's disease."


Alzheimer's WA Chairman Adjunct Professor Warren Harding said the findings may have a significant global impact for the millions of people living with Alzheimer's disease.




Story Source:


Materials provided by Curtin University.



Thursday, September 23, 2021

In Case You Missed It...9/24


American Carnage, Steve Bannon


TRUMP WORLD MADNESS


RELEASE THE SUBPOENAS 

PELOSI'S STRATEGY       

MAGA MASK MENACE


INVEST IN US

BIDEN PRESSES FELLOW DEMS: FIND YOUR WAY TO ‘YES’ AND GET IT DONE

PELOSI SIGNALS SHE WON’T MOVE RECONCILIATION BILL WITHOUT SENATE DEAL; WON’T BE SCREWED BY SENATE LIKE IN 2010

 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Hudson, former president, National Association of Former Foster Children


ELIMINATE THE DEBT CEILING


OMB ISSUES SHUTDOWN INSTRUCTIONS (JUST IN CASE)

WHY BIDEN ISN’T HITTING THE PANIC BUTTON ON THE DEBT CEILING — YET

 

COVID CRISIS ROLLS ON


ICU CRISIS IN BILLINGS, MONTANA: WE ARE RUNNING OUT OF HALLWAY SPACE!

MICHAEL FLYNN SPREADS BIZARRE CONSPIRACY THEORY ABOUT VACCINES IN SALAD DRESSING

FLORIDA GOVERNOR DESANTIS SAYS PARENTS CAN SEND ASYMPTOMATIC KIDS EXPOSED TO COVID-19 BACK TO SCHOOL


AMERICA’S POLICING PROBLEMS
THE GEORGE FLOYD JUSTICE IN POLICING ACT IS DEAD

BIDEN, HARRIS CRITICIZE SENATE REPUBLICANS FOR TANKING BIPARTISAN POLICE REFORM TALKS

FROM THE ARCHIVES: WHAT THE “DEFUND THE POLICE” SLOGAN REALLY MEANS

WHAT THE REST OF AMERICA CAN LEARN FROM COLORADO’S POLICE REFORMS

In Case You Missed It...9/23

 

The New Journalism...by Book

TRUMP: "DANGEROUS MAN, DANGEROUS PRESIDENT"


FIGHTING FOR PROGRESS


HOUSE PASSES BILL TO AVERT SHUTDOWN AND SUSPEND DEBT CEILING, BUT FACES UNCERTAIN FUTURE IN THE SENATE

INFRASTRUCTURE, DEBT, AND TRILLIONS IN SPENDING: WHERE CONGRESS STANDS ON KEY DEADLINES

PRO-TAX BILLIONAIRES SUPPORT PROGRESSIVE CAUCUS; CALL FOR REJECTION OF INFRASTRUCTURE PACKAGE WITHOUT RECONCILIATION PLAN

HOUSE DEMOCRATIC LEADERSHIP TO PUT THE SCREWS TO PHARMA-BACKED CENTRISTS SO DEMOCRATS CAN REDUCE PRICES OF PRESCRIPTION DRUGS

 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Hudson, former president, National Association of Former Foster Children


BIPARTISAN INFRASTRUCTURE BILL VOTE LIKELY TO FAIL ON FIRST VOTE; WILL BE DELAYED AND COME BACK FOR A SECOND VOTE

THE ONLY LANGUAGE MCCONNELL UNDERSTANDS IS POWER. DEMOCRATS MUST ACT ACCORDINGLY.

 

LIARS & TRAITORS
RIGHT-WING LAWYER PENNED 6-PAGE MEMO ON HOW PENCE COULD HAND THE 2020 ELECTION TO TRUMP, BY NOT ACCEPTING SLATES OF ELECTORS

TRUMP-ERA WHITE HOUSE MEMO SHOWS TRUMP TEAM KNEW CLAIMS AGAINST DOMINION VOTING MACHINES WERE A LIE

SMARTMATIC SOFTWARE SMEARS WERE ALSO A LIE – THEIR SOFTWARE WAS IN USE IN EXACTLY ONE COUNTY IN 2020

FLASHBACK NOV 2020: RUDY GIULIANI WORKED HARD TO DO RUSSIA’S DISINFORMATION WORK FOR THEM

FORMER TRUMP DEPUTY CAMPAIGN MANAGER DAVID BOSSIE FELT THAT SIDNEY POWELL WAS PEDDLING ‘CONCOCTED BULLSH**’ ABOUT 2020 ELECTION

Wednesday, September 22, 2021

In case You Missed It...9/21

 



U.S. Senate/Senator Joe Manchin...
Democracy in his hands?

COLBERT INTERVIEWS WOODWARD, COSTA

DEMOCRACY HANGING BY A THREAD

NY TIMES ON REPUBLICAN VOTER SUPRESSION

A "HEIGHTENED SENSE OF THREAT"


 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Hudson, former president, National Association of Former Foster Children


BORDER CRISIS


SEC. MAYORKAS: DHS TO OPEN INVESTIGATION AFTER IMAGES SHOW AGENTS ON HORSEBACK GRABBING MIGRANTS

WHITE HOUSE SAYS OF IMAGE OF BORDER AGENT WHIPPING AT HAITIAN MIGRANT ‘HORRIBLE TO WATCH’, AND NOT APPROPRIATE


REPUBLICAN WAR ON WOMEN

SUPREME COURT TO HEAR RESTRICTIVE MISSISSIPPI ABORTION LAW ON DECEMBER 1

ALAN BRAID PREFORMED A TEXAS ABORTION IN VIOLATION OF TEXAS LAW


Monday, September 20, 2021

In Case You Missed It...9/20

 

White House/It's Do or Die Time for Biden

CONGRESS IS BACK – WITH A MOUNTAIN OF WORK TO DO


CONGRESS RETURNS TO WORK FACING MAJOR DECISIONS ON VOTING RIGHTS, INFRASTRUCTURE, & THE DEBT LIMIT

BIDEN – AND DEMOCRATS – ENTIRE AGENDA HANGS ON ONE PAIR OF BILLS

THE CHANCE TO IMPROVE OUR HEALTH CARE SYSTEM – INCL. HOME HEALTH CARE, PAY FOR HEARING AIDS, & GET DENTAL COVERAGE – ALL ON THE LINE

HUNGRY IN AMERICA: MORE AMERICANS STRUGGLING TO PUT FOOD ON THE TABLE AFTER FEDERAL COVID BENEFITS END

A REMINDER FOR ANYONE SCREAMING ABOUT THE DEBT: TRUMP & REPUBLICANS ADDED $7T IN DEBT BEFORE THE PANDEMIC

FIVE QUESTIONS AND ANSWERS ABOUT THE DEBT CEILING FIGHT

DEMS BEST CHANCE TO PASS DEBT LIMIT MAYBE TO TIE IT TO DISASTER RELIEF – AND PUSH OFF PASSAGE UNTIL OCTOBER

THE TRILLION DOLLAR COIN IDEA IS BACK: DEMS & BIDEN COULD SIDESTEP REPUBLICAN REFUSAL TO PAY AMERICA’S BILLS BY MINTING UNIQUE COIN

JOE MANCHIN GOT THE VOTING BILL HE WANTED. TIME FOR HIM TO MAKE SURE IT GETS PASSED.

SKEWED COVERAGE OF BIDEN

 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Hudson, former president, National Association of Former Foster Children 


THE REVOLVING DOOR
REVOLVING CORRUPTION: FMR. SENS. HEITKAMP AND DONNELLY’S RURAL VOTER PROJECT TIED TO MEDICARE FOR ALL OPPONENTS

JOE MANCHIN, THE SENATE’S TOP RECIPIENT OF OIL, GAS, & COAL DONATIONS IS NOW WRITING THE CLIMATE PORTION THE RECONCILIATION BILL

KYRSTEN SINEMA, ONE OF CONGRESS’ LEADING RECIPIENTS OF BIG PHARMA DONATIONS, TELLS WH SHE’S AGAINST PLAN TO REDUCE PRICES OF PRESCRIPTION DRUGS

 

THE PARTISAN & ILLIGITIMATE SUPREME COURT
THE REPUBLICAN-LED SENATE KNEW ABOUT KAVANAUGH’S PARTISAN HISTORY & CONFIRMED HIM ANYWAY.

MONSTERS WHO AUTHORED TEXAS’ DISASTROUS ABORTION LAW ALSO AIM TO HAVE SCOTUS USE IT TO BAN GAY MARRIAGE AND GAY SEX

Credit, RandiRhodes.com

Saturday, September 18, 2021

In Case You Missed It...9/18


Vanity Fair/Florida Gov. Ron Death Santis. New King of Covid.


FLORIDA PASSES GRIM MILESTONE: 50,000 DEAD FROM COVID

FLORIDA REPUBLICAN OFFICIAL WHO CALLED COVID A “PLANDEMIC” CONSPIRACY DIES FROM COVID-19

DEATH OF FL GOP OFFICAL CAUSES FINANCIAL PROBLEMS FOR PARTY; HIS FRIEND CALLS CITY COUNCIL TO REPORT “ILLEGAL INTUBATION”

DESANTIS OPENS NEW WAR WITH BIDEN OVER COVID TREATMENTS

COUNTER TO RIGHT-WING PROPAGANDA, BIDEN ADMINISTRATION MOVING TO STAVE OFF SHORTAGES OF MONOCLONAL ANTIBODIES

FLORIDA SURGEON GENERAL DOESN’T WANT TO TESTIFY ABOUT MASK MANDATE

MISSISSIPPI NOW HAS COUNTRY’S HIGHEST RATE FOR COVID DEATHS

IDAHO IS IN STATEWIDE MASS-CASUALTY TRIAGE MODE

BOOSTER OR NOT: WHAT TO EXPECT AS FDA ADVISORY PANEL DEBATES PFIZER COVID BOOSTER SHOTS

 



Healing the Brain: Stress, Trauma and Development


“Easy to read. Difficult to put down.”--Micheal J. Colucciello, Jr., NY State pharmaceutical researcher, retired.

“David Balog takes a subject fraught with difficulty and makes it simple and accessible to everyone. The book goes a long way in helping one understand how and why and in what ways stress affects how we live and cope. Invaluable.”--Jessica Watson-Crosby, former president, National Association of Former Foster Children


INSURRECTIONISTS BAWL
DEBUNKING THE PRO-TRUMP RIGHT’S CLAIMS ABOUT THE JAN. 6 RIOT

TRUMP EXPRESSES SOLIDARITY WITH JAN 6 TERRORISTS AHEAD OF PLANNED SEPT 18 RALLY SUPPORTING INSURRECTIONISTS

SATURDAY’S RALLY ORGANIZER IS A FAILED TRUMP CAMPAIGN STAFFER


Credit: Randirhodes.com